San Diego Startup Ecosystem
Biotech hub with defense tech, healthcare, and enterprise software focus. Strong research institutions and UCSD talent.
Ecosystem Overview
💰 Funding
$2.5B+ in total funding, with strong access to VCs and research grants.
👥 Talent
100K+ tech workers and access to UCSD and research institutions.
🏢 Infrastructure
10 accelerators, 20 co-working spaces, and strong research institutions.
Key Strengths
Key Industries
Cost of Living
Top Accelerators
Top Funding Sources
Notable Companies
Frequently Asked Questions
Why is San Diego a good city for startups?
San Diego offers a strong biotech hub with defense tech, healthcare, and enterprise software focus, strong research institutions (UCSD), lower costs than SF/LA, and attractive lifestyle. The city has a strong presence in biotech, defense tech, and healthcare, with access to UCSD talent and research.
What are the top accelerators in San Diego?
Top accelerators include EvoNexus, Techstars San Diego, and Connect. The ecosystem also benefits from strong UCSD connections and research partnerships. Many accelerators focus on biotech and life sciences.
How much does it cost to start a startup in San Diego?
San Diego has a cost of living index of 160 (60% above national average), making it more expensive than many cities but more affordable than SF/LA. Average rent for a 1-bedroom is around $2,200/month. However, the access to biotech talent and research often justifies the cost for relevant startups.
What industries are strongest in San Diego?
San Diego is particularly strong in biotech, defense tech, healthcare, and enterprise software. The city's position as a major biotech hub with strong research institutions makes it ideal for biotech and life sciences startups.
Is San Diego good for biotech startups?
Yes, San Diego is one of the best cities for biotech startups due to its position as a major biotech hub, proximity to UCSD and research institutions, strong biotech talent pool, and growing biotech ecosystem. The city is home to many biotech companies and research institutions.
What VCs are active in San Diego?
Active VCs include Avalon Ventures, Forward Ventures, and Correlation Ventures. Many national VCs also invest in San Diego startups, recognizing the opportunities in biotech and the value proposition of strong research talent and lower costs than SF.
Compare with Other Ecosystems
🏛️ Boston
World's leading biotech hub. Higher costs but more established ecosystem.
Compare →🔬 Raleigh/Durham
Similar biotech focus. Lower costs and strong research institutions.
Compare →🌴 Los Angeles
Similar California location. Higher costs but more diverse industries.
Compare →☕ Seattle
Similar enterprise software focus. Similar costs and tech giants.
Compare →