🔔PHILADELPHIA ECOSYSTEM

Philadelphia Startup Ecosystem

Emerging startup ecosystem with strong universities, healthcare focus, and growing tech scene. Lower costs and access to major markets.

1,000+ startups2 unicornsLast updated: January 2025

Ecosystem Overview

💰 Funding

$1.5B+ in total funding, with growing access to VCs and angel investors.

👥 Talent

70K+ tech workers and access to UPenn, Temple, and Drexel talent.

🏢 Infrastructure

8 accelerators, 15 co-working spaces, and growing support networks.

Key Strengths

Strong universities (UPenn, Temple, Drexel)Healthcare and medtech focusLower costs compared to major citiesGrowing tech sceneAccess to major marketsBusiness-friendly environment

Key Industries

Healthcare TechEnterprise SoftwareFintechEdTechE-commerceReal Estate Tech

Cost of Living

$1,500/mo
Average 1BR Rent
$2,000/mo
Average 2BR Rent
110
Cost of Living Index (100 = National Average)

Frequently Asked Questions

Why is Philadelphia a good city for startups?

Philadelphia offers an emerging startup ecosystem with strong universities, healthcare focus, lower costs than major tech hubs, access to major markets, and growing tech scene. The city has a strong presence in healthcare, fintech, and enterprise software, with access to university talent.

What are the top accelerators in Philadelphia?

Top accelerators include Dreamit Ventures, Ben Franklin Technology Partners, and 1776. The ecosystem also benefits from strong university connections (UPenn, Drexel) and growing startup community. Many accelerators focus on healthcare and fintech.

How much does it cost to start a startup in Philadelphia?

Philadelphia has a cost of living index of 101 (1% above national average), making it one of the most affordable major startup hubs. Average rent for a 1-bedroom is around $1,300/month, allowing startups to significantly extend their runway while accessing university talent.

What industries are strongest in Philadelphia?

Philadelphia is particularly strong in healthcare, fintech, and enterprise software. The city's position as a major healthcare hub with strong universities makes it ideal for healthcare tech startups. Strong financial services presence supports fintech innovation.

Is Philadelphia good for healthcare startups?

Yes, Philadelphia is one of the best cities for healthcare startups due to its position as a major healthcare hub, proximity to major healthcare companies, strong healthcare talent pool from UPenn and other universities, and growing healthcare tech ecosystem.

What VCs are active in Philadelphia?

Active VCs include First Round Capital, Osage Venture Partners, and Ben Franklin Technology Partners. Many national VCs also invest in Philadelphia startups, recognizing the opportunities in healthcare and the value proposition of lower costs and strong university talent.